Significant Differences in Physicochemical Properties of Human Immunoglobulin Kappa and Lambda CDR3 Regions

Antibody variable regions are composed of a heavy and a light chain, and in humans, there are two light chain isotypes: kappa and lambda. Despite their importance in receptor editing, the light chain is often overlooked in the antibody literature, with the focus being on the heavy chain complementar...

Descripción completa

Detalles Bibliográficos
Autores principales: Townsend, Catherine L., Laffy, Julie M. J., Wu, Yu-Chang Bryan, Silva O’Hare, Joselli, Martin, Victoria, Kipling, David, Fraternali, Franca, Dunn-Walters, Deborah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037968/
https://www.ncbi.nlm.nih.gov/pubmed/27729912
http://dx.doi.org/10.3389/fimmu.2016.00388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037968/
https://www.ncbi.nlm.nih.gov/pubmed/27729912
http://dx.doi.org/10.3389/fimmu.2016.00388

Ejemplares similares