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Germline Variation in Superoxide Dismutase-2 (SOD2) and Survival Outcomes after Radiation Therapy for Prostate Cancer: Results from a Test and Validation Set Analysis

BACKGROUND: Genetic variants in antioxidant pathways may decrease the efficacy of radiation therapy (RT) by suppressing the generation of reactive oxygen species (ROS). We studied the association between single nucleotide polymorphisms (SNPs) in the antioxidant gene superoxide dismutase-2 (SOD2) and...

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Detalles Bibliográficos
Autores principales: Margalit, Danielle N., Jordahl, Kristina M., Werner, Lillian, Wang, Xiaodong, Lee, Mary Gwo-Shu, Penney, Kathryn L., Batista, Julie L., Martin, Neil E., Chan, June M., Kantoff, Philip W., Stampfer, Meir J., Nguyen, Paul L., Mucci, Lorelei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038132/
https://www.ncbi.nlm.nih.gov/pubmed/25662905
http://dx.doi.org/10.1016/j.clgc.2014.12.018