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Establishment of ApoE-knockout mouse model of preeclampsia and relevant mechanisms

In the present study, we established an ApoE-knockout mouse model of preeclampsia to examine the role of vascular endothelial injury associated with abnormal lipid metabolism in the pathogenesis of preeclampsia. To establish the ApoE-knockout homozygous (ApoE(−/−)) and heterozygous (ApoE(+/−)) mouse...

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Detalles Bibliográficos
Autores principales: Sun, Wenjuan, Cui, Baoxia, Hong, Fanzhen, Xu, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038201/
https://www.ncbi.nlm.nih.gov/pubmed/27698766
http://dx.doi.org/10.3892/etm.2016.3678