Glutamate Racemase Is the Primary Target of β-Chloro-d-Alanine in Mycobacterium tuberculosis

The increasing global prevalence of drug resistance among many leading human pathogens necessitates both the development of antibiotics with novel mechanisms of action and a better understanding of the physiological activities of preexisting clinically effective drugs. Inhibition of peptidoglycan (P...

Descripción completa

Detalles Bibliográficos
Autores principales: Prosser, Gareth A., Rodenburg, Anne, Khoury, Hania, de Chiara, Cesira, Howell, Steve, Snijders, Ambrosius P., de Carvalho, Luiz Pedro S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038272/
https://www.ncbi.nlm.nih.gov/pubmed/27480853
http://dx.doi.org/10.1128/AAC.01249-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038272/
https://www.ncbi.nlm.nih.gov/pubmed/27480853
http://dx.doi.org/10.1128/AAC.01249-16

Ejemplares similares