Amikacin Optimal Exposure Targets in the Hollow-Fiber System Model of Tuberculosis

Aminoglycosides such as amikacin are currently used for the treatment of multidrug-resistant tuberculosis (MDR-TB). However, formal pharmacokinetic/pharmacodynamic (PK/PD) studies to identify amikacin exposures and dosing schedules that optimize Mycobacterium tuberculosis killing have not been perfo...

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Detalles Bibliográficos
Autores principales: Srivastava, Shashikant, Modongo, Chawanga, Siyambalapitiyage Dona, Chandima W., Pasipanodya, Jotam G., Deshpande, Devyani, Gumbo, Tawanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038304/
https://www.ncbi.nlm.nih.gov/pubmed/27458215
http://dx.doi.org/10.1128/AAC.00961-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038304/
https://www.ncbi.nlm.nih.gov/pubmed/27458215
http://dx.doi.org/10.1128/AAC.00961-16

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