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Amikacin Optimal Exposure Targets in the Hollow-Fiber System Model of Tuberculosis

Aminoglycosides such as amikacin are currently used for the treatment of multidrug-resistant tuberculosis (MDR-TB). However, formal pharmacokinetic/pharmacodynamic (PK/PD) studies to identify amikacin exposures and dosing schedules that optimize Mycobacterium tuberculosis killing have not been perfo...

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Detalles Bibliográficos
Autores principales:	Srivastava, Shashikant, Modongo, Chawanga, Siyambalapitiyage Dona, Chandima W., Pasipanodya, Jotam G., Deshpande, Devyani, Gumbo, Tawanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038304/ https://www.ncbi.nlm.nih.gov/pubmed/27458215 http://dx.doi.org/10.1128/AAC.00961-16

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