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Increase of T and B cells and altered BACH2 expression patterns in bone marrow trephines of imatinib-treated patients with chronic myelogenous leukaemia

The effect of imatinib on T and B cells in patients with chronic myelogenous leukaemia (CML) is not well understood. An upregulation of the transcription factor Broad-complex-Tramtrack-Bric-a-Brac and Cap‘n’collar 1 bZip transcription factor 2 (BACH2), which is involved in the development and differ...

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Detalles Bibliográficos
Autores principales: Von Laffert, Maximilian, Hänel, Mathias, Dietel, Manfred, Anagnostopoulos, Ioannis, Jöhrens, Korinna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038374/
https://www.ncbi.nlm.nih.gov/pubmed/27698808
http://dx.doi.org/10.3892/ol.2016.4964