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Fluorescence in situ hybridization testing of chromosomes 6, 8, 9 and 11 in melanocytic tumors is difficult to automate and reveals tumor heterogeneity in melanomas

Malignant melanomas may be difficult to differentiate from benign nevi on the basis of histology. Contrary to nevi, the majority of melanomas harbor chromosomal imbalances. Comparative genomic hybridization-based and fluorescence in situ hybridization (FISH) tests can help differentiating malignant...

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Detalles Bibliográficos
Autores principales: Uguen, Arnaud, Uguen, Marie, Talagas, Matthieu, Gobin, Eric, Marcorelles, Pascale, De Braekeleer, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038458/
https://www.ncbi.nlm.nih.gov/pubmed/27698849
http://dx.doi.org/10.3892/ol.2016.4949