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LSKL peptide alleviates subarachnoid fibrosis and hydrocephalus by inhibiting TSP1-mediated TGF-β1 signaling activity following subarachnoid hemorrhage in rats

Hydrocephalus has been demonstrated to be an independent risk factor for poor outcomes in patients with subarachnoid hemorrhage (SAH). Blockage of cerebrospinal fluid (CSF) flow and drainage is widely considered to play a vital role in communicating hydrocephalus, possibly due to subarachnoid fibros...

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Detalles Bibliográficos
Autores principales: Liao, Fan, Li, Gaofeng, Yuan, Wen, Chen, Yujie, Zuo, Yuchun, Rashid, Kauthar, Zhang, John H., Feng, Hua, Liu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038515/
https://www.ncbi.nlm.nih.gov/pubmed/27698755
http://dx.doi.org/10.3892/etm.2016.3640