17AAG-induced internalisation of HER2-specific Affibody molecules

The geldanamycin derivative 17-allylamino-17-demethoxygeldanamycin (17-AAG) is known to induce internalisation and degradation of the otherwise internalisation-resistant human epidermal growth factor receptor 2 (HER2) receptor. In the present study, 17-AAG was used to increase internalisation of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Göstring, Lovisa, Lindegren, Sture, Gedda, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038849/
https://www.ncbi.nlm.nih.gov/pubmed/27698830
http://dx.doi.org/10.3892/ol.2016.4990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038849/
https://www.ncbi.nlm.nih.gov/pubmed/27698830
http://dx.doi.org/10.3892/ol.2016.4990

Ejemplares similares