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Ethanol and High Cholesterol Diet Causes Severe Steatohepatitis and Early Liver Fibrosis in Mice

BACKGROUND AND AIM: Because ethanol consumption is commonly associated with a high cholesterol diet, we examined whether combined consumption of ethanol and high cholesterol increases liver injury and fibrosis. METHODS: Male C57BL/6J mice were fed diets containing: 1) 35% of calories from corn oil (...

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Detalles Bibliográficos
Autores principales: Krishnasamy, Yasodha, Ramshesh, Venkat K., Gooz, Monika, Schnellmann, Rick G., Lemasters, John J., Zhong, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038945/
https://www.ncbi.nlm.nih.gov/pubmed/27676640
http://dx.doi.org/10.1371/journal.pone.0163342