Data-Driven Metabolic Pathway Compositions Enhance Cancer Survival Prediction

Altered cellular metabolism is an important characteristic and driver of cancer. Surprisingly, however, we find here that aggregating individual gene expression using canonical metabolic pathways fails to enhance the classification of noncancerous vs. cancerous tissues and the prediction of cancer p...

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Detalles Bibliográficos
Autores principales: Auslander, Noam, Wagner, Allon, Oberhardt, Matthew, Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038951/
https://www.ncbi.nlm.nih.gov/pubmed/27673682
http://dx.doi.org/10.1371/journal.pcbi.1005125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038951/
https://www.ncbi.nlm.nih.gov/pubmed/27673682
http://dx.doi.org/10.1371/journal.pcbi.1005125

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