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Data-Driven Metabolic Pathway Compositions Enhance Cancer Survival Prediction
Altered cellular metabolism is an important characteristic and driver of cancer. Surprisingly, however, we find here that aggregating individual gene expression using canonical metabolic pathways fails to enhance the classification of noncancerous vs. cancerous tissues and the prediction of cancer p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038951/ https://www.ncbi.nlm.nih.gov/pubmed/27673682 http://dx.doi.org/10.1371/journal.pcbi.1005125 |