Cargando…

DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk

The aminopeptidase DPP9 removes dipeptides from N-termini of substrates having a proline or alanine in second position. Although linked to several pathways including cell survival and metabolism, the molecular mechanisms underlying these outcomes are poorly understood. We identified a novel interact...

Descripción completa

Detalles Bibliográficos
Autores principales: Justa-Schuch, Daniela, Silva-Garcia, Maria, Pilla, Esther, Engelke, Michael, Kilisch, Markus, Lenz, Christof, Möller, Ulrike, Nakamura, Fumihiko, Urlaub, Henning, Geiss-Friedlander, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039030/
https://www.ncbi.nlm.nih.gov/pubmed/27614019
http://dx.doi.org/10.7554/eLife.16370