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Large-scale profiling of signalling pathways reveals an asthma specific signature in bronchial smooth muscle cells

BACKGROUND: Bronchial smooth muscle (BSM) cells from asthmatic patients maintain in vitro a distinct hyper-reactive (“primed”) phenotype, characterized by increased release of pro-inflammatory factors and mediators, as well as hyperplasia and/or hypertrophy. This “primed” phenotype helps to understa...

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Detalles Bibliográficos
Autores principales: Alexandrova, Elena, Nassa, Giovanni, Corleone, Giacomo, Buzdin, Anton, Aliper, Alexander M., Terekhanova, Nadezhda, Shepelin, Denis, Zhavoronkov, Alexander, Tamm, Michael, Milanesi, Luciano, Miglino, Nicola, Weisz, Alessandro, Borger, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039037/
https://www.ncbi.nlm.nih.gov/pubmed/26863634
http://dx.doi.org/10.18632/oncotarget.7209