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Protein/DNA interactions in complex DNA topologies: expect the unexpected

DNA supercoiling results in compacted DNA structures that can bring distal sites into close proximity. It also changes the local structure of the DNA, which can in turn influence the way it is recognised by drugs, other nucleic acids and proteins. Here, we discuss how DNA supercoiling and the format...

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Detalles Bibliográficos
Autores principales: Noy, Agnes, Sutthibutpong, Thana, A. Harris, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039213/
https://www.ncbi.nlm.nih.gov/pubmed/27738452
http://dx.doi.org/10.1007/s12551-016-0208-8