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Effects of DNA supercoiling on chromatin architecture

Disruptions in chromatin structure are necessary for the regulation of eukaryotic genomes, from remodelling of nucleosomes at the base pair level through to large-scale chromatin domains that are hundreds of kilobases in size. RNA polymerase is a powerful motor which, prevented from turning with the...

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Detalles Bibliográficos
Autores principales: Corless, Samuel, Gilbert, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039215/
https://www.ncbi.nlm.nih.gov/pubmed/27738453
http://dx.doi.org/10.1007/s12551-016-0210-1