Incision-Dependent and Error-Free Repair of (CAG)(n)/(CTG)(n) Hairpins in Human Cell Extracts

Expansion of CAG/CTG trinucleotide repeats is associated with certain familial neurological disorders, including Huntington's disease. Increasing evidence suggests that formation of a stable DNA hairpin within CAG/CTG repeats during DNA metabolism contributes to their expansion. However, the mo...

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Detalles Bibliográficos
Autores principales: Hou, Caixia, Chan, Nelson L.S., Gu, Liya, Li, Guo-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039229/
https://www.ncbi.nlm.nih.gov/pubmed/19597480
http://dx.doi.org/10.1038/nsmb.1638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039229/
https://www.ncbi.nlm.nih.gov/pubmed/19597480
http://dx.doi.org/10.1038/nsmb.1638

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