Cargando…
Incision-Dependent and Error-Free Repair of (CAG)(n)/(CTG)(n) Hairpins in Human Cell Extracts
Expansion of CAG/CTG trinucleotide repeats is associated with certain familial neurological disorders, including Huntington's disease. Increasing evidence suggests that formation of a stable DNA hairpin within CAG/CTG repeats during DNA metabolism contributes to their expansion. However, the mo...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039229/ https://www.ncbi.nlm.nih.gov/pubmed/19597480 http://dx.doi.org/10.1038/nsmb.1638 |