Myricitrin Protects against Doxorubicin-Induced Cardiotoxicity by Counteracting Oxidative Stress and Inhibiting Mitochondrial Apoptosis via ERK/P53 Pathway

Doxorubicin (Dox) is one of the most effective and widely used anthracycline antineoplastic antibiotics. Unfortunately, the use of Dox is limited by its cumulative and dose-dependent cardiac toxicity. Myricitrin, a natural flavonoid which is isolated from the ground bark of Myrica rubra, has recentl...

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Detalles Bibliográficos
Autores principales: Sun, Jing, Sun, Guibo, Cui, Xiaolan, Meng, Xiangbao, Qin, Meng, Sun, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039279/
https://www.ncbi.nlm.nih.gov/pubmed/27703489
http://dx.doi.org/10.1155/2016/6093783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039279/
https://www.ncbi.nlm.nih.gov/pubmed/27703489
http://dx.doi.org/10.1155/2016/6093783

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