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Myricitrin Protects against Doxorubicin-Induced Cardiotoxicity by Counteracting Oxidative Stress and Inhibiting Mitochondrial Apoptosis via ERK/P53 Pathway
Doxorubicin (Dox) is one of the most effective and widely used anthracycline antineoplastic antibiotics. Unfortunately, the use of Dox is limited by its cumulative and dose-dependent cardiac toxicity. Myricitrin, a natural flavonoid which is isolated from the ground bark of Myrica rubra, has recentl...
Autores principales: | Sun, Jing, Sun, Guibo, Cui, Xiaolan, Meng, Xiangbao, Qin, Meng, Sun, Xiaobo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039279/ https://www.ncbi.nlm.nih.gov/pubmed/27703489 http://dx.doi.org/10.1155/2016/6093783 |
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