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Reversal of Vascular Calcification and Aneurysms in a Rat Model Using Dual Targeted Therapy with EDTA- and PGG-Loaded Nanoparticles

Degeneration of elastic lamina and vascular calcification are common features of vascular pathology such as aortic aneurysms. We tested whether dual therapy with targeted nanoparticles (NPs) can remove mineral deposits (by delivery of a chelating agent, ethylene diamine tetraacetic acid (EDTA)) and...

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Detalles Bibliográficos
Autores principales: Nosoudi, Nasim, Chowdhury, Aniqa, Siclari, Steven, Karamched, Saketh, Parasaram, Vaideesh, Parrish, Joe, Gerard, Patrick, Vyavahare, Narendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039337/
https://www.ncbi.nlm.nih.gov/pubmed/27698934
http://dx.doi.org/10.7150/thno.16547