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An Integrated Analysis of the Genome-Wide Profiles of DNA Methylation and mRNA Expression Defining the Side Population of a Human Malignant Mesothelioma Cell Line

Intratumoral heterogeneity is a hallmark of all cancers and functions as the major barrier against effective cancer therapy. In contrast to genetic mutations, the role of epigenetic modifications in the generation and maintenance of heterogeneous cancer cells remains largely undetermined. This study...

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Detalles Bibliográficos
Autores principales: Kim, Myung-Chul, Kim, Na-Yon, Seo, Yu-Ri, Kim, Yongbaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039388/
https://www.ncbi.nlm.nih.gov/pubmed/27698904
http://dx.doi.org/10.7150/jca.15423