Aberrant Glycosylation of Anchor-Optimized MUC1 Peptides Can Enhance Antigen Binding Affinity and Reverse Tolerance to Cytotoxic T Lymphocytes

Cancer vaccines have often failed to live up to their promise, although recent results with checkpoint inhibitors are reviving hopes that they will soon fulfill their promise. Although mutation-specific vaccines are under development, there is still high interest in an off-the-shelf vaccine to a ubi...

Descripción completa

Detalles Bibliográficos
Autores principales: Pathangey, Latha B., Lakshminarayanan, Vani, Suman, Vera J., Pockaj, Barbara A., Mukherjee, Pinku, Gendler, Sandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039417/
https://www.ncbi.nlm.nih.gov/pubmed/27367740
http://dx.doi.org/10.3390/biom6030031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039417/
https://www.ncbi.nlm.nih.gov/pubmed/27367740
http://dx.doi.org/10.3390/biom6030031

Ejemplares similares