2-O-Acyl-3-O-(1-acyloxyalkyl) Prodrugs of 5,6-Isopropylidene-l-Ascorbic Acid and l-Ascorbic Acid: Antioxidant Activity and Ability to Permeate Silicone Membranes

2-O-Acyl-3-O-(1-acyloxyalkyl) prodrug derivatives, 15, of 5,6-isopropylidene-l-ascorbic acid, VCA, and l-ascorbic acid, VC, have been characterized by measuring (1) their solubilities in water (S(AQ)) and in 1-octanol (S(OCT)); (2) the ability of one member of the homologous series, 15a, to diffuse...

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Detalles Bibliográficos
Autores principales: Thiele, Nikki A., McGowan, Jennifer, Sloan, Kenneth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039441/
https://www.ncbi.nlm.nih.gov/pubmed/27438850
http://dx.doi.org/10.3390/pharmaceutics8030022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039441/
https://www.ncbi.nlm.nih.gov/pubmed/27438850
http://dx.doi.org/10.3390/pharmaceutics8030022

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