Site-Specific Labeling of Protein Kinase CK2: Combining Surface Display and Click Chemistry for Drug Discovery Applications †

Human CK2 is a heterotetrameric constitutively active serine/threonine protein kinase and is an emerging target in current anti-cancer drug discovery. The kinase is composed of two catalytic CK2α subunits and two regulatory CK2β subunits. In order to establish an assay to identify protein-protein-in...

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Detalles Bibliográficos
Autores principales: Nienberg, Christian, Retterath, Anika, Becher, Kira-Sophie, Saenger, Thorsten, Mootz, Henning D., Jose, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039489/
https://www.ncbi.nlm.nih.gov/pubmed/27355959
http://dx.doi.org/10.3390/ph9030036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039489/
https://www.ncbi.nlm.nih.gov/pubmed/27355959
http://dx.doi.org/10.3390/ph9030036

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