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Odanacatib, a Cathepsin K Cysteine Protease Inhibitor, Kills Hookworm In Vivo

Hookworm infection is chief among soil-transmitted helminthiases (STHs) for the chronic morbidly inflicted. Deworming via mass drug administration (MDA) programs most often employs single doses of benzimidazole drugs to which resistance is a constant threat. To discover new drugs, we employ a hamste...

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Detalles Bibliográficos
Autores principales: Vermeire, Jon J., Suzuki, Brian M., Caffrey, Conor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039492/
https://www.ncbi.nlm.nih.gov/pubmed/27384569
http://dx.doi.org/10.3390/ph9030039