Cargando…

Convergent Synthesis of Two Fluorescent Ebselen-Coumarin Heterodimers

The organo-seleniumdrug ebselen exhibits a wide range of pharmacological effects that are predominantly due to its interference with redox systems catalyzed by seleno enzymes, e.g., glutathione peroxidase and thioredoxin reductase. Moreover, ebselen can covalently interact with thiol groups of sever...

Descripción completa

Detalles Bibliográficos
Autores principales: Küppers, Jim, Schulz-Fincke, Anna Christina, Palus, Jerzy, Giurg, Mirosław, Skarżewski, Jacek, Gütschow, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039496/
https://www.ncbi.nlm.nih.gov/pubmed/27399725
http://dx.doi.org/10.3390/ph9030043