Biotin Protein Ligase Is a Target for New Antibacterials

There is a desperate need for novel antibiotic classes to combat the rise of drug resistant pathogenic bacteria, such as Staphylococcus aureus. Inhibitors of the essential metabolic enzyme biotin protein ligase (BPL) represent a promising drug target for new antibacterials. Structural and biochemica...

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Detalles Bibliográficos
Autores principales: Feng, Jiage, Paparella, Ashleigh S., Booker, Grant W., Polyak, Steven W., Abell, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039522/
https://www.ncbi.nlm.nih.gov/pubmed/27463729
http://dx.doi.org/10.3390/antibiotics5030026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039522/
https://www.ncbi.nlm.nih.gov/pubmed/27463729
http://dx.doi.org/10.3390/antibiotics5030026

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