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Biotin Protein Ligase Is a Target for New Antibacterials

There is a desperate need for novel antibiotic classes to combat the rise of drug resistant pathogenic bacteria, such as Staphylococcus aureus. Inhibitors of the essential metabolic enzyme biotin protein ligase (BPL) represent a promising drug target for new antibacterials. Structural and biochemica...

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Detalles Bibliográficos
Autores principales:	Feng, Jiage, Paparella, Ashleigh S., Booker, Grant W., Polyak, Steven W., Abell, Andrew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039522/ https://www.ncbi.nlm.nih.gov/pubmed/27463729 http://dx.doi.org/10.3390/antibiotics5030026

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