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From Erythromycin to Azithromycin and New Potential Ribosome-Binding Antimicrobials
Macrolides, as a class of natural or semisynthetic products, express their antibacterial activity primarily by reversible binding to the bacterial 50S ribosomal subunits and by blocking nascent proteins’ progression through their exit tunnel in bacterial protein biosynthesis. Generally considered to...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039525/ https://www.ncbi.nlm.nih.gov/pubmed/27598215 http://dx.doi.org/10.3390/antibiotics5030029 |