Design and Synthesis of Analogues of Marine Natural Product Galaxamide, an N-methylated Cyclic Pentapeptide, as Potential Anti-Tumor Agent in Vitro

Herein, we report design and synthesis of novel 26 galaxamide analogues with N-methylated cyclo-pentapeptide, and their in vitro anti-tumor activity towards the panel of human tumor cell line, such as, A549, A549/DPP, HepG2 and SMMC-7721 using MTT assay. We have also investigated the effect of galax...

Descripción completa

Detalles Bibliográficos
Autores principales: Lunagariya, Jignesh, Zhong, Shenghui, Chen, Jianwei, Bai, Defa, Bhadja, Poonam, Long, Weili, Liao, Xiaojian, Tang, Xiaoli, Xu, Shihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039532/
https://www.ncbi.nlm.nih.gov/pubmed/27598177
http://dx.doi.org/10.3390/md14090161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039532/
https://www.ncbi.nlm.nih.gov/pubmed/27598177
http://dx.doi.org/10.3390/md14090161

Ejemplares similares