Cargando…

Depletion of primary cilia from mature dentate granule cells impairs hippocampus-dependent contextual memory

The primary cilium, a sensory organelle, regulates cell proliferation and neuronal development of dentate granule cells in the hippocampus. However, its role in the function of mature dentate granule cells remains unknown. Here we specifically depleted and disrupted ciliary proteins IFT20 and Kif3A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rhee, Soyoung, Kirschen, Gregory W., Gu, Yan, Ge, Shaoyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039642/ https://www.ncbi.nlm.nih.gov/pubmed/27678193 http://dx.doi.org/10.1038/srep34370

Ejemplares similares

Lateral dispersion is required for circuit integration of newly generated dentate granule cells
por: Wang, Jia, et al.
Publicado: (2019)

Early Dendritic Morphogenesis of Adult-Born Dentate Granule Cells Is Regulated by FHL2
por: Ahamad, Afrinash, et al.
Publicado: (2020)

Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus
por: Choi, Moonseok, et al.
Publicado: (2016)

Temporally selective contextual encoding in the dentate gyrus of the hippocampus
por: Rangel, L.M., et al.
Publicado: (2014)

The temporal origin of dentate granule neurons dictates their role in spatial memory
por: Masachs, Nuria, et al.
Publicado: (2021)

Dentate granule cells encode auditory decisions after reinforcement learning in rats
por: Shen, Jia, et al.
Publicado: (2021)

Optical controlling reveals time-dependent roles for adult-born dentate granule cells
por: Gu, Yan, et al.
Publicado: (2012)

Plasticity of intrinsic excitability in mature granule cells of the dentate gyrus
por: Lopez-Rojas, Jeffrey, et al.
Publicado: (2016)

Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness
por: Kohen, R, et al.
Publicado: (2014)

TWIK-1 contributes to the intrinsic excitability of dentate granule cells in mouse hippocampus
por: Yarishkin, Oleg, et al.
Publicado: (2014)

Parvalbumin interneurons provide spillover to newborn and mature dentate granule cells
por: Vaden, Ryan J, et al.
Publicado: (2020)

Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampus
por: Han, Kyung-Seok, et al.
Publicado: (2011)

Modeling Contextual Modulation of Memory Associations in the Hippocampus
por: Pilly, Praveen K., et al.
Publicado: (2018)

Facilitating Granule Cell Survival and Maturation in Dentate Gyrus With Baicalin for Antidepressant Therapeutics
por: Zhao, Fan, et al.
Publicado: (2020)

Lentiviral silencing of GSK-3β in adult dentate gyrus impairs contextual fear memory and synaptic plasticity
por: Chew, Benjamin, et al.
Publicado: (2015)

Primary cilia as a novel horizon between neuron and environment
por: Kirschen, Gregory W., et al.
Publicado: (2017)

Nectin-3 modulates the structural plasticity of dentate granule cells and long-term memory
por: Wang, X-X, et al.
Publicado: (2017)

Progression in Time of Dentate Gyrus Granule Cell Layer Widening due to Excitotoxicity Occurs along In Vivo LTP Reinstatement and Contextual Fear Memory Recovery
por: Hernández Mercado, Karina, et al.
Publicado: (2022)

Status epilepticus increases mature granule cells in the molecular layer of the dentate gyrus in rats★
por: Liang, Zhaoliang, et al.
Publicado: (2013)

Tactile modulation of memory and anxiety requires dentate granule cells along the dorsoventral axis
por: Wang, Chi, et al.
Publicado: (2020)

Shifted Dynamics of Glucose Metabolism in the Hippocampus During Aging
por: Ge, Ivan, et al.
Publicado: (2021)

Rapid erasure of hippocampal memory following inhibition of dentate gyrus granule cells
por: Madroñal, Noelia, et al.
Publicado: (2016)

Editorial: Changes in metabolic processes affecting brain development
por: Kirschen, Gregory W., et al.
Publicado: (2022)

Schizophrenia-associated SAP97 mutations increase glutamatergic synapse strength in the dentate gyrus and impair contextual episodic memory in rats
por: Kay, Yuni, et al.
Publicado: (2022)

Cdk5 Regulates Accurate Maturation of Newborn Granule Cells in the Adult Hippocampus
por: Jessberger, Sebastian, et al.
Publicado: (2008)

Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus
por: Ohira,, Koji, et al.
Publicado: (2010)

Age-Dependent Degeneration of Mature Dentate Gyrus Granule Cells Following NMDA Receptor Ablation
por: Watanabe, Yasuhito, et al.
Publicado: (2016)

Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination
por: Jones, Brian W, et al.
Publicado: (2016)

Anisomycin injection in area CA3 of the hippocampus impairs both short-term and long-term memories of contextual fear
por: Remaud, Jessica, et al.
Publicado: (2014)

Loss of Ensemble Segregation in Dentate Gyrus, but not in Somatosensory Cortex, during Contextual Fear Memory Generalization
por: Yokoyama, Marie, et al.
Publicado: (2016)

Adiponectin regulates contextual fear extinction and intrinsic excitability of dentate gyrus granule neurons through AdipoR2 receptors
por: Zhang, D, et al.
Publicado: (2017)

5-HT1A Receptors on Mature Dentate Gyrus Granule Cells are Critical for the Antidepressant Response
por: Samuels, Benjamin Adam, et al.
Publicado: (2015)

Chronic corticosterone administration reduces dendritic complexity in mature, but not young granule cells in the rat dentate gyrus
por: Yau, Suk-Yu, et al.
Publicado: (2016)

Congenital hypothyroidism impairs spine growth of dentate granule cells by downregulation of CaMKIV
por: Tang, Qingying, et al.
Publicado: (2021)

The Hippocampal Neuro-Glio-Vascular Network: Metabolic Vulnerability and Potential Neurogenic Regeneration in Disease
por: Kirschen, Gregory W., et al.
Publicado: (2018)

Neurons of the Dentate Molecular Layer in the Rabbit Hippocampus
por: Sancho-Bielsa, Francisco J., et al.
Publicado: (2012)

Striatal and midbrain connectivity with the hippocampus selectively boosts memory for contextual novelty
por: Kafkas, Alexandros, et al.
Publicado: (2015)

PEGylated Carbon Nanotubes Impair Retrieval of Contextual Fear Memory and Alter Oxidative Stress Parameters in the Rat Hippocampus
por: Dal Bosco, Lidiane, et al.
Publicado: (2015)

Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization
por: Guo, Nannan, et al.
Publicado: (2018)

The Low-Threshold Calcium Channel Cav3.2 Mediates Burst Firing of Mature Dentate Granule Cells
por: Dumenieu, Mael, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8445fgt3qh6qak57uksnavpe5t