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Erianin inhibits high glucose-induced retinal angiogenesis via blocking ERK1/2-regulated HIF-1α-VEGF/VEGFR2 signaling pathway

Erianin is a natural compound found in Dendrobium chrysotoxum Lindl. Diabetic retinopathy (DR) is a serious and common microvascular complication of diabetes. This study aims to investigate the inhibitory mechanism of erianin on retinal neoangiogenesis and its contribution to the amelioration of DR....

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Detalles Bibliográficos
Autores principales: Yu, Zengyang, Zhang, Tianyu, Gong, Chenyuan, Sheng, Yuchen, Lu, Bin, Zhou, Lingyu, Ji, Lili, Wang, Zhengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039671/
https://www.ncbi.nlm.nih.gov/pubmed/27678303
http://dx.doi.org/10.1038/srep34306