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Proto-Oncogenic Src Phosphorylates EB1 to Regulate the Microtubule-Focal Adhesion Crosstalk and Stimulate Cell Migration

Cell migration, a complex process critical for tumor progression and metastasis, requires a dynamic crosstalk between microtubules (MTs) and focal adhesions (FAs). However, the molecular mechanisms underlying this event remain elusive. Herein we identify the proto-oncogenic protein Src as an importa...

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Detalles Bibliográficos
Autores principales: Zhang, Yijun, Luo, Youguang, Lyu, Rui, Chen, Jie, Liu, Ruming, Li, Dengwen, Liu, Min, Zhou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039685/
https://www.ncbi.nlm.nih.gov/pubmed/27698945
http://dx.doi.org/10.7150/thno.16356