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Persistence of fan-shaped keratocytes is a matrix-rigidity-dependent mechanism that requires α(5)β(1) integrin engagement

Despite the importance of matrix rigidity on cell functions, many aspects of the mechanosensing process in highly migratory cells remain elusive. Here, we studied the migration of highly motile keratocytes on culture substrates with similar biochemical properties and rigidities spanning the range be...

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Detalles Bibliográficos
Autores principales: Riaz, Maryam, Versaevel, Marie, Mohammed, Danahe, Glinel, Karine, Gabriele, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039689/
https://www.ncbi.nlm.nih.gov/pubmed/27678055
http://dx.doi.org/10.1038/srep34141