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The role of Rad51 in safeguarding mitochondrial activity during the meiotic cell cycle in mammalian oocytes
Rad51 is a conserved eukaryotic protein that mediates the homologous recombination repair of DNA double-strand breaks that occur during mitosis and meiosis. In addition, Rad51 promotes mitochondrial DNA synthesis when replication stress is increased. Rad51 also regulates cell cycle progression by pr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039699/ https://www.ncbi.nlm.nih.gov/pubmed/27677401 http://dx.doi.org/10.1038/srep34110 |