Non-cell autonomous cues for enhanced functionality of human embryonic stem cell-derived cardiomyocytes via maturation of sarcolemmal and mitochondrial K(ATP) channels

Human embryonic stem cells (hESCs) is a potential unlimited ex vivo source of ventricular (V) cardiomyocytes (CMs), but hESC-VCMs and their engineered tissues display immature traits. In adult VCMs, sarcolemmal (sarc) and mitochondrial (mito) ATP-sensitive potassium (K(ATP)) channels play crucial ro...

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Detalles Bibliográficos
Autores principales: Keung, Wendy, Ren, Lihuan, Sen Li, Wong, Andy On-Tik, Chopra, Anant, Kong, Chi-Wing, Tomaselli, Gordon F., Chen, Christopher S., Li, Ronald A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039730/
https://www.ncbi.nlm.nih.gov/pubmed/27677332
http://dx.doi.org/10.1038/srep34154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039730/
https://www.ncbi.nlm.nih.gov/pubmed/27677332
http://dx.doi.org/10.1038/srep34154

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