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Adenylyl cyclase 3 haploinsufficiency confers susceptibility to diet-induced obesity and insulin resistance in mice

Adenylyl cyclase 3 (Adcy3), a member of the mammalian adenylyl cyclase family responsible for generating the second messenger cAMP, has long been known to play an essential role in olfactory signal transduction. Here, we demonstrated that Adcy3 heterozygous null mice displayed increased visceral adi...

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Detalles Bibliográficos
Autores principales: Tong, Tao, Shen, Ying, Lee, Han-Woong, Yu, Rina, Park, Taesun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039768/
https://www.ncbi.nlm.nih.gov/pubmed/27678003
http://dx.doi.org/10.1038/srep34179