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Dasatinib enhances tumor growth in gemcitabine-resistant orthotopic bladder cancer xenografts
BACKGROUND: Systemic chemotherapy with gemcitabine and cisplatin is standard of care for patients with metastatic urothelial bladder cancer. However, resistance formation is common after initial response. The protein Src is known as a proto-oncogene, which is overexpressed in various human cancers....
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039786/ https://www.ncbi.nlm.nih.gov/pubmed/27677700 http://dx.doi.org/10.1186/s13104-016-2256-3 |