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Influence of dosing times on cisplatin-induced peripheral neuropathy in rats

BACKGROUND: Although cis-diamminedichloro-platinum (CDDP) exhibits strong therapeutic effects in cancer chemotherapy, its adverse effects such as peripheral neuropathy, nephropathy, and vomiting are dose-limiting factors. Previous studies reported that chronotherapy decreased CDDP-induced nephropath...

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Detalles Bibliográficos
Autores principales: Seto, Yoshihiro, Okazaki, Fumiyasu, Horikawa, Keiji, Zhang, Jing, Sasaki, Hitoshi, To, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039788/
https://www.ncbi.nlm.nih.gov/pubmed/27678475
http://dx.doi.org/10.1186/s12885-016-2777-0