Extracellular ATP is involved in dsRNA-induced MUC5AC production via P2Y2R in human airway epithelium

BACKGROUND: In response to tissue damage or inflammation, adenosine-5′-triphosphate (ATP) is released into the extracellular compartment and has been demonstrated to augment inflammation via purinergic P2 receptors (P2Rs). Recently, ATP has been shown to be increased in the airways of COPD patients....

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Detalles Bibliográficos
Autores principales: Shishikura, Yutaka, Koarai, Akira, Aizawa, Hiroyuki, Yamaya, Mutsuo, Sugiura, Hisatoshi, Watanabe, Mika, Hashimoto, Yuichiro, Numakura, Tadahisa, Makiguti, Tomonori, Abe, Kyoko, Yamada, Mituhiro, Kikuchi, Toshiaki, Hoshikawa, Yasushi, Okada, Yoshinori, Ichinose, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039824/
https://www.ncbi.nlm.nih.gov/pubmed/27677339
http://dx.doi.org/10.1186/s12931-016-0438-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039824/
https://www.ncbi.nlm.nih.gov/pubmed/27677339
http://dx.doi.org/10.1186/s12931-016-0438-0

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