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A drug target slim: using gene ontology and gene ontology annotations to navigate protein-ligand target space in ChEMBL

BACKGROUND: The process of discovering new drugs is a lengthy, time-consuming and expensive process. Modern day drug discovery relies heavily on the rapid identification of novel ‘targets’, usually proteins that can be modulated by small molecule drugs to cure or minimise the effects of a disease. O...

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Detalles Bibliográficos
Autores principales: Mutowo, Prudence, Bento, A. Patrícia, Dedman, Nathan, Gaulton, Anna, Hersey, Anne, Lomax, Jane, Overington, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039825/
https://www.ncbi.nlm.nih.gov/pubmed/27678076
http://dx.doi.org/10.1186/s13326-016-0102-0