The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms

BACKGROUND: Neuroblastoma is a relatively common and highly belligerent childhood tumor with poor prognosis by current therapeutic approaches. A novel anti-cancer agent of the di-2-pyridylketone thiosemicarbazone series, namely di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT), demonstrat...

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Detalles Bibliográficos
Autores principales: Guo, Zhu-Ling, Richardson, Des R., Kalinowski, Danuta S., Kovacevic, Zaklina, Tan-Un, Kian Cheng, Chan, Godfrey Chi-Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039880/
https://www.ncbi.nlm.nih.gov/pubmed/27678372
http://dx.doi.org/10.1186/s13045-016-0330-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039880/
https://www.ncbi.nlm.nih.gov/pubmed/27678372
http://dx.doi.org/10.1186/s13045-016-0330-x

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