Time-resolved dual RNA-seq reveals extensive rewiring of lung epithelial and pneumococcal transcriptomes during early infection

BACKGROUND: Streptococcus pneumoniae, the pneumococcus, is the main etiological agent of pneumonia. Pneumococcal infection is initiated by bacterial adherence to lung epithelial cells. The exact transcriptional changes occurring in both host and microbe during infection are unknown. Here, we develop...

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Detalles Bibliográficos
Autores principales: Aprianto, Rieza, Slager, Jelle, Holsappel, Siger, Veening, Jan-Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039909/
https://www.ncbi.nlm.nih.gov/pubmed/27678244
http://dx.doi.org/10.1186/s13059-016-1054-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039909/
https://www.ncbi.nlm.nih.gov/pubmed/27678244
http://dx.doi.org/10.1186/s13059-016-1054-5

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