Rapid and powerful detection of subtle allelic imbalance from exome sequencing data with hapLOHseq

Motivation: The detection of subtle genomic allelic imbalance events has many potential applications. For example, identifying cancer-associated allelic imbalanced regions in low tumor-cellularity samples or in low-proportion tumor subclones can be used for early cancer detection, prognostic assessm...

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Detalles Bibliográficos
Autores principales: San Lucas, F. Anthony, Sivakumar, Smruthy, Vattathil, Selina, Fowler, Jerry, Vilar, Eduardo, Scheet, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039922/
https://www.ncbi.nlm.nih.gov/pubmed/27288500
http://dx.doi.org/10.1093/bioinformatics/btw340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039922/
https://www.ncbi.nlm.nih.gov/pubmed/27288500
http://dx.doi.org/10.1093/bioinformatics/btw340

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