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Rapid and powerful detection of subtle allelic imbalance from exome sequencing data with hapLOHseq
Motivation: The detection of subtle genomic allelic imbalance events has many potential applications. For example, identifying cancer-associated allelic imbalanced regions in low tumor-cellularity samples or in low-proportion tumor subclones can be used for early cancer detection, prognostic assessm...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039922/ https://www.ncbi.nlm.nih.gov/pubmed/27288500 http://dx.doi.org/10.1093/bioinformatics/btw340 |