Production of infectious HCV genotype 1b virus in cell culture using a novel Set of adaptive mutations

BACKGROUND: Despite the high prevalence of genotype 1b hepatitis C virus (HCV) among patients, a cell culture system that permits entire viral life cycle of genotype 1b isolates is limited. To develop a cell-cultured hepatitis C virus (HCVcc) of genotype 1b, the proper combination of HCV genomic var...

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Detalles Bibliográficos
Autores principales: Mori, Ken-ichi, Matsumoto, Akihiro, Maki, Noboru, Ichikawa, Yuki, Tanaka, Eiji, Yagi, Shintaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039931/
https://www.ncbi.nlm.nih.gov/pubmed/27678340
http://dx.doi.org/10.1186/s12866-016-0846-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039931/
https://www.ncbi.nlm.nih.gov/pubmed/27678340
http://dx.doi.org/10.1186/s12866-016-0846-9

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