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Gamma-aminobutyric acid aggravates nephrotoxicity induced by cisplatin in female rats

Introduction: Cisplatin (CP) is a major antineoplastic drug for treatment of solid tumors. CP-induced nephrotoxicity may be gender-related. This is while gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter in the central nervous system that has renoprotective impacts on acute renal inju...

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Detalles Bibliográficos
Autores principales: Peysepar, Elham, Soltani, Nepton, Nematbakhsh, Mehdi, Eshraghi-Jazi, Fatemeh, Talebi, Ardeshir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nickan Research Institute 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039987/
https://www.ncbi.nlm.nih.gov/pubmed/27689121
http://dx.doi.org/10.15171/jrip.2016.40