Exposing the Three-Dimensional Biogeography and Metabolic States of Pathogens in Cystic Fibrosis Sputum via Hydrogel Embedding, Clearing, and rRNA Labeling

Physiological resistance to antibiotics confounds the treatment of many chronic bacterial infections, motivating researchers to identify novel therapeutic approaches. To do this effectively, an understanding of how microbes survive in vivo is needed. Though much can be inferred from bulk approaches...

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Detalles Bibliográficos
Autores principales: DePas, William H., Starwalt-Lee, Ruth, Van Sambeek, Lindsey, Ravindra Kumar, Sripriya, Gradinaru, Viviana, Newman, Dianne K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040109/
https://www.ncbi.nlm.nih.gov/pubmed/27677788
http://dx.doi.org/10.1128/mBio.00796-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040109/
https://www.ncbi.nlm.nih.gov/pubmed/27677788
http://dx.doi.org/10.1128/mBio.00796-16

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